Definition - What does 5-Tuple mean?
A 5-tuple refers to a set of five different values that comprise a Transmission Control Protocol/Internet Protocol (TCP/IP) connection. It includes a source IP address/port number, destination IP address/port number and the protocol in use.
Techopedia explains 5-Tuple
System and network administrators (NA) use 5-tuples to identify key requirements for creating a secure, operational and bidirectional network connection between two or more remote and local machines.
The source and destination addresses are primary 5-tuple components. The source address is the IP address of the network that creates and sends a data packet, and the destination address is the recipient.